Andrographis paniculata is one of the most popular Indian medicinal herb used traditionally for the treatment of array of diseases as cancer, diabetes, high blood pressure, ulcers, leprosy, bronchitis, skin diseases, flatulence, colic, influenza, dysentery, dyspepsia and malaria for centuries in Asia, America and African continents. It possesses several photochemical constituents with unique biological properties. Extract and pure compounds of this plant has been reported for their anti-microbial, cytotoxicity, anti-protozoan, anti-inflammatory, anti-antioxidant, immunostimulant, anti-diabetic, anti-infective, anti-angiogenic, hepato-renal protective, sex hormone/sexual function modulation, liver enzymes modulation insecticidal and toxicity activities.

Andrographis paniculata has been extensively used as a traditional medicine in India, China, and Southeast Asia. The aerial parts of possess most of the medicinal properties and are used to treat snakebites, insect strings, fever, sore throat, cough and stomachache. Phytochemical study revealed that diterpenoid lactones and flavonoids have been isolated from the aerial parts of this specie. Miscellaneous compounds have also been extracted from the roots with differing activities. In addition, clinical and laboratory studies on the toxicity effect help us understand its safety and eligibility as a source of modern herbal medicine.

This work was in part supported by a Fulbright Award granted to Dr. A. Falodun for study at University of Mississippi; and University of Benin Research.